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Substitute of lumigan 0.01 eye drops (0.06) or 2 (0.1, 0.4, 0.8, 1.2, or 2 mg/kg) by the intraocular lens of eye was effective to reduce myopia (Fig. 1, Table IV, and V). The maximum effect was observed during the first 1 week, which doses of Lumigan 2 mg/kg twice daily were not effective for reducing myopia. On this basis, the doses of Lumigan 2 mg/kg (10 mg every days) that were administered daily to children 2 years of age and older were more cost-effective than those Prednisone 20 mg generic of Lumigan eye drops used in the same age group, i.e., less costly. However, the efficacy of lumigan eye drops increased with the age at which they are used and declined sharply during the last 3 months and prior to the date of study. A decline in the effectiveness of Lumigan eye drops was more rapid than that observed for the intraocular lens preparations; efficacy with the eye drops continued to improve with increasing age and was approximately the same in both youngest children and oldest children. Figure 1 View largeDownload slide Effect-size plots of myopia reduction by various ophthalmic preparations. The x, y axis represents change in myopia unit time after 1 or 3 8 weeks of treatment with each preparation. (A) 1,000 μl/day lumigan eyedrop and (B or C) 2,000 μl/day dimetazidine eyedrop were effective for reducing myopia (mean value: 3.9, 1.4, 0.9, 0.5, and 3 mm Hg; n = 24 in the sample). Each treatment has 2 SDs within the interval of mean value. For example, a value greater than 3 mm Hg may indicate a treatment that is better for certain individuals than others. Table IV Variable Study period and dose (mg/kg) Follow-up (months) Mean effect size, % Dose adjustment for age, No treatment (n = 24) 0–6 months 36) 1,000 μl/day Lumigan 2 mg/kg (n = 14) 0.5 3.9 6 months to 3 years (n = 10) 5,000 μl/day Lumigan 2 mg/kg or 0.0575 mg/4 ml dimetazidine eyedrop (n = 6) 1 7.2 3 years to and then (3–6 years, n = 10) 3,500 μl/day Lumigan 2 mg/kg or 0.0575 mg/4 ml dimetazidine eyedrop (n = 6) 1 8.2 3 years to and then (3–6 years, n = 10) 10,000 μl/day Lumigan 3 mg/kg (n = 4) 9.8 7.6 4–5 years and (n = 10) 5,000 μl/day Lumigan 2 mg/kg or 0.0575 mg/4 ml dimetazidine eyedrop (n = 7) 1 2.4 5–6 years and (n = 10) 6,500 μl/day Lumigan Acido valproico 200 mg precio 2 mg/kg or 0.0575 mg/4 ml dimetazidine eyedrop (n = 9) 2 6.5 Mean difference, ± SE (n = 8) 6.5 mm Hg Mean difference, ± SE (n = 8) 4.7 mm Hg Variable Study period and dose (mg/kg) Follow-up (months) Mean effect size, % Dose adjustment for age, No treatment (n = 24) 0–6 months 36) 1,000 μl/day Lumigan 2 mg/kg (n = 14) 0.5 3.9 6 months to 3 years (n = 10) 5,000 μl/day Lumigan 2 mg/kg or 0.0575 mg/4 ml dimetazidine eyedrop (n = 6) 1 7.2 3 years to and then (3–6 years,.
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